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Tumor hypoxia is associated with resistance to PD-1 blockade in squamous cell carcinoma of the head and neck
The majority of patients with recurrent/metastatic squamous cell carcinoma of the head and neck (HNSCC) (R/M) do not benefit from anti-PD-1 therapy. Hypoxia induced immunosuppression may be a barrier to immunotherapy. Therefore, we examined the metabolic effect of anti-PD-1 therapy in a murine MEER...
Sparad:
| I publikationen: | J Immunother Cancer |
|---|---|
| Huvudupphovsmän: | , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
BMJ Publishing Group
2021
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8126285/ https://ncbi.nlm.nih.gov/pubmed/33986123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-002088 |
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