Chargement en cours...
Tumor cell oxidative metabolism as a barrier to PD-1 blockade immunotherapy in melanoma
The tumor microenvironment presents physical, immunologic, and metabolic barriers to durable immunotherapy responses. We have recently described roles for both T cell metabolic insufficiency as well as tumor hypoxia as inhibitory mechanisms that prevent T cell activity in murine tumors, but whether...
Enregistré dans:
| Publié dans: | JCI Insight |
|---|---|
| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
2019
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6483505/ https://ncbi.nlm.nih.gov/pubmed/30721155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124989 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|