Death agonist antibody against TRAILR2/DR5/TNFRSF10B enhances birinapant anti-tumor activity in HPV-positive head and neck squamous cell carcinomas

Head and neck squamous cell carcinomas (HNSCC) induced by human papillomavirus (HPV) have increased recently in the US. However, the distinct alterations of molecules involved in the death pathways and drug effects targeting inhibitor of apoptosis proteins (IAPs) have not been extensively characteri...

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Bibliographic Details
Published in:Sci Rep
Main Authors: An, Yi, Jeon, Jun, Sun, Lillian, Derakhshan, Adeeb, Chen, Jianhong, Carlson, Sophie, Cheng, Hui, Silvin, Christopher, Yang, Xinping, Van Waes, Carter, Chen, Zhong
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7973748/
https://ncbi.nlm.nih.gov/pubmed/33737574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-85589-5
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