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Death agonist antibody against TRAILR2/DR5/TNFRSF10B enhances birinapant anti-tumor activity in HPV-positive head and neck squamous cell carcinomas

Head and neck squamous cell carcinomas (HNSCC) induced by human papillomavirus (HPV) have increased recently in the US. However, the distinct alterations of molecules involved in the death pathways and drug effects targeting inhibitor of apoptosis proteins (IAPs) have not been extensively characteri...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: An, Yi, Jeon, Jun, Sun, Lillian, Derakhshan, Adeeb, Chen, Jianhong, Carlson, Sophie, Cheng, Hui, Silvin, Christopher, Yang, Xinping, Van Waes, Carter, Chen, Zhong
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7973748/
https://ncbi.nlm.nih.gov/pubmed/33737574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-85589-5
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