Death agonist antibody against TRAILR2/DR5/TNFRSF10B enhances birinapant anti-tumor activity in HPV-positive head and neck squamous cell carcinomas

Head and neck squamous cell carcinomas (HNSCC) induced by human papillomavirus (HPV) have increased recently in the US. However, the distinct alterations of molecules involved in the death pathways and drug effects targeting inhibitor of apoptosis proteins (IAPs) have not been extensively characteri...

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Publicado no:Sci Rep
Main Authors: An, Yi, Jeon, Jun, Sun, Lillian, Derakhshan, Adeeb, Chen, Jianhong, Carlson, Sophie, Cheng, Hui, Silvin, Christopher, Yang, Xinping, Van Waes, Carter, Chen, Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7973748/
https://ncbi.nlm.nih.gov/pubmed/33737574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-85589-5
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