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Cryo-EM structure of the Rous sarcoma virus octameric cleaved synaptic complex intasome
Despite conserved catalytic integration mechanisms, retroviral intasomes composed of integrase (IN) and viral DNA possess diverse structures with variable numbers of IN subunits. To investigate intasome assembly mechanisms, we employed the Rous sarcoma virus (RSV) IN dimer that assembles a precursor...
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| Publicado no: | Commun Biol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7955051/ https://ncbi.nlm.nih.gov/pubmed/33712691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01855-2 |
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