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Cryo-EM structure of the Rous sarcoma virus octameric cleaved synaptic complex intasome

Despite conserved catalytic integration mechanisms, retroviral intasomes composed of integrase (IN) and viral DNA possess diverse structures with variable numbers of IN subunits. To investigate intasome assembly mechanisms, we employed the Rous sarcoma virus (RSV) IN dimer that assembles a precursor...

詳細記述

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書誌詳細
出版年:Commun Biol
主要な著者: Pandey, Krishan K., Bera, Sibes, Shi, Ke, Rau, Michael J., Oleru, Amarachi V., Fitzpatrick, James A. J., Engelman, Alan N., Aihara, Hideki, Grandgenett, Duane P.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955051/
https://ncbi.nlm.nih.gov/pubmed/33712691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01855-2
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