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A C-terminal “Tail” Region in the Rous Sarcoma Virus Integrase Provides High Plasticity of Functional Integrase Oligomerization during Intasome Assembly

The retrovirus integrase (IN) inserts the viral cDNA into the host DNA genome. Atomic structures of five different retrovirus INs complexed with their respective viral DNA or branched viral/target DNA substrates have indicated these intasomes are composed of IN subunits ranging from tetramers, to oc...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Pandey, Krishan K., Bera, Sibes, Shi, Ke, Aihara, Hideki, Grandgenett, Duane P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377814/
https://ncbi.nlm.nih.gov/pubmed/28184005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.773382
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