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Differential assembly of Rous sarcoma virus tetrameric and octameric intasomes is regulated by the C-terminal domain and tail region of integrase

Retrovirus integrase (IN) catalyzes the concerted integration of linear viral DNA ends into chromosomes. The atomic structures of five different retrovirus IN–DNA complexes, termed intasomes, have revealed varying IN subunit compositions ranging from tetramers to octamers, dodecamers, and hexadecame...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Bera, Sibes, Pandey, Krishan K., Aihara, Hideki, Grandgenett, Duane P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200937/
https://ncbi.nlm.nih.gov/pubmed/30185621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004768
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