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Cryo-EM structure of the Rous sarcoma virus octameric cleaved synaptic complex intasome
Despite conserved catalytic integration mechanisms, retroviral intasomes composed of integrase (IN) and viral DNA possess diverse structures with variable numbers of IN subunits. To investigate intasome assembly mechanisms, we employed the Rous sarcoma virus (RSV) IN dimer that assembles a precursor...
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| Publicado en: | Commun Biol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7955051/ https://ncbi.nlm.nih.gov/pubmed/33712691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01855-2 |
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