Reconstructing the Lineage Histories and Differentiation Trajectories of Individual Cancer Cells in Myeloproliferative Neoplasms

Some cancers originate from a single mutation event in a single cell. Blood cancers known as myeloproliferative neoplasms (MPNs) are thought to originate when a driver mutation is acquired by a hematopoietic stem cell (HSC). However, when the mutation first occurs in individuals and how it affects t...

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Опубликовано в: :Cell Stem Cell
Главные авторы: Van Egeren, Debra, Escabi, Javier, Nguyen, Maximilian, Liu, Shichen, Reilly, Christopher R., Patel, Sachin, Kamaz, Baransel, Kalyva, Maria, DeAngelo, Daniel J., Galinsky, Ilene, Wadleigh, Martha, Winer, Eric S., Luskin, Marlise R., Stone, Richard M., Garcia, Jacqueline S., Hobbs, Gabriela S., Camargo, Fernando D., Michor, Franziska, Mullally, Ann, Cortes-Ciriano, Isidro, Hormoz, Sahand
Формат: Artigo
Язык:Inglês
Опубликовано: Cell Press 2021
Предметы:
Short Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939520/
https://ncbi.nlm.nih.gov/pubmed/33621486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2021.02.001
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