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Integrating readout of somatic mutations in individual cells with single-cell transcriptional profiling

In many biological applications, the readout of somatic mutations in individual cells is essential. For example, it can be used to mark individual cancer cells or identify progenies of a stem cell. Here, we present a protocol to perform single-cell RNA-seq and single-cell amplicon-seq using 10X Chro...

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Detalhes bibliográficos
Publicado no:STAR Protoc
Main Authors: Liu, Shichen, Nguyen, Maximilian, Hormoz, Sahand
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8313752/
https://ncbi.nlm.nih.gov/pubmed/34337442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100673
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