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Integrating readout of somatic mutations in individual cells with single-cell transcriptional profiling

In many biological applications, the readout of somatic mutations in individual cells is essential. For example, it can be used to mark individual cancer cells or identify progenies of a stem cell. Here, we present a protocol to perform single-cell RNA-seq and single-cell amplicon-seq using 10X Chro...

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Bibliografiska uppgifter
I publikationen:STAR Protoc
Huvudupphovsmän: Liu, Shichen, Nguyen, Maximilian, Hormoz, Sahand
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8313752/
https://ncbi.nlm.nih.gov/pubmed/34337442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100673
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