Reconstructing the Lineage Histories and Differentiation Trajectories of Individual Cancer Cells in Myeloproliferative Neoplasms

Some cancers originate from a single mutation event in a single cell. Blood cancers known as myeloproliferative neoplasms (MPNs) are thought to originate when a driver mutation is acquired by a hematopoietic stem cell (HSC). However, when the mutation first occurs in individuals and how it affects t...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Van Egeren, Debra, Escabi, Javier, Nguyen, Maximilian, Liu, Shichen, Reilly, Christopher R., Patel, Sachin, Kamaz, Baransel, Kalyva, Maria, DeAngelo, Daniel J., Galinsky, Ilene, Wadleigh, Martha, Winer, Eric S., Luskin, Marlise R., Stone, Richard M., Garcia, Jacqueline S., Hobbs, Gabriela S., Camargo, Fernando D., Michor, Franziska, Mullally, Ann, Cortes-Ciriano, Isidro, Hormoz, Sahand
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2021
Assuntos:
Short Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7939520/
https://ncbi.nlm.nih.gov/pubmed/33621486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2021.02.001
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