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Structure and Regulation of Phospholipase Cβ and ε at the Membrane

Phospholipase C (PLC) β and ε enzymes hydrolyze phosphatidylinositol (PI) lipids in response to direct interactions with heterotrimeric G protein subunits and small GTPases activated downstream of G protein-coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs). PI hydrolysis generates secon...

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Publicado en:Chem Phys Lipids
Main Authors: Muralidharan, Kaushik, Van Camp, Michelle M., Lyon, Angeline M.
Formato: Artigo
Idioma:Inglês
Publicado: 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7933103/
https://ncbi.nlm.nih.gov/pubmed/33422547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemphyslip.2021.105050
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