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Functional and structural characterization of allosteric activation of phospholipase Cε by Rap1A
Phospholipase Cε (PLCε) is activated downstream of G protein–coupled receptors and receptor tyrosine kinases through direct interactions with small GTPases, including Rap1A and Ras. Although Ras has been reported to allosterically activate the lipase, it is not known whether Rap1A has the same abili...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7864056/ https://ncbi.nlm.nih.gov/pubmed/32948655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015685 |
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