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Structural Insights into Phospholipase C-β Function

Phospholipase C (PLC) enzymes convert phosphatidylinositol-4,5-bisphosphate into the second messengers diacylglycerol and inositol-1,4,5-triphosphate. The production of these molecules promotes the release of intracellular calcium and activation of protein kinase C, which results in profound cellula...

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Detalhes bibliográficos
Main Authors: Lyon, Angeline M., Tesmer, John J. G.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781385/
https://ncbi.nlm.nih.gov/pubmed/23880553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.087403
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