載入...
Inhibitor design to target a unique feature in the folate pocket of Staphylococcus aureus dihydrofolate reductase
Staphylococcus aureus (Sa) is a serious concern due to increasing resistance to antibiotics. The bacterial dihydrofolate reductase enzyme is effectively inhibited by trimethoprim, a compound with antibacterial activity. Previously, we reported a trimethoprim derivative containing an acryloyl linker...
Na minha lista:
| 發表在: | Eur J Med Chem |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2020
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7932028/ https://ncbi.nlm.nih.gov/pubmed/32502861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2020.112412 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|