The Role of NLRP3 Inflammasome in Pericarditis: Potential for Therapeutic Approaches

Human samples of patients with chronic pericarditis and appropriate control subjects were stained for the inflammasome components. A mouse model of pericarditis was developed through the intrapericardial injection of zymosan A. Different inflammasome blockers were tested in the mouse model. Patients...

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Foilsithe in:JACC Basic Transl Sci
Main Authors: Mauro, Adolfo G., Bonaventura, Aldo, Vecchié, Alessandra, Mezzaroma, Eleonora, Carbone, Salvatore, Narayan, Pratyush, Potere, Nicola, Cannatà, Antonio, Paolini, John F., Bussani, Rossana, Montecucco, Fabrizio, Sinagra, Gianfranco, Van Tassel, Benjamin W., Abbate, Antonio, Toldo, Stefano
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2021
Ábhair:
Preclinical Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907621/
https://ncbi.nlm.nih.gov/pubmed/33665514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2020.11.016
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