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Inflammasome formation in the lungs of patients with fatal COVID-19
OBJECTIVE: The orf8b protein of the coronavirus SARS-CoV, analogous to SARS-CoV-2, triggers the NLRP3 inflammasome in macrophages in vitro. Deregulated inflammasome-mediated release of interleukin-1 family cytokines is important in hyper-inflammatory syndromes, like happens in SARS-CoV-2-mediated cy...
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| Publicado no: | Inflamm Res |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7572246/ https://ncbi.nlm.nih.gov/pubmed/33079210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00011-020-01413-2 |
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