The Role of NLRP3 Inflammasome in Pericarditis: Potential for Therapeutic Approaches

Human samples of patients with chronic pericarditis and appropriate control subjects were stained for the inflammasome components. A mouse model of pericarditis was developed through the intrapericardial injection of zymosan A. Different inflammasome blockers were tested in the mouse model. Patients...

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Udgivet i:JACC Basic Transl Sci
Main Authors: Mauro, Adolfo G., Bonaventura, Aldo, Vecchié, Alessandra, Mezzaroma, Eleonora, Carbone, Salvatore, Narayan, Pratyush, Potere, Nicola, Cannatà, Antonio, Paolini, John F., Bussani, Rossana, Montecucco, Fabrizio, Sinagra, Gianfranco, Van Tassel, Benjamin W., Abbate, Antonio, Toldo, Stefano
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021
Fag:
Preclinical Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907621/
https://ncbi.nlm.nih.gov/pubmed/33665514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2020.11.016
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