The Role of NLRP3 Inflammasome in Pericarditis: Potential for Therapeutic Approaches

Human samples of patients with chronic pericarditis and appropriate control subjects were stained for the inflammasome components. A mouse model of pericarditis was developed through the intrapericardial injection of zymosan A. Different inflammasome blockers were tested in the mouse model. Patients...

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Detalhes bibliográficos
Publicado no:JACC Basic Transl Sci
Main Authors: Mauro, Adolfo G., Bonaventura, Aldo, Vecchié, Alessandra, Mezzaroma, Eleonora, Carbone, Salvatore, Narayan, Pratyush, Potere, Nicola, Cannatà, Antonio, Paolini, John F., Bussani, Rossana, Montecucco, Fabrizio, Sinagra, Gianfranco, Van Tassel, Benjamin W., Abbate, Antonio, Toldo, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Preclinical Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907621/
https://ncbi.nlm.nih.gov/pubmed/33665514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2020.11.016
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