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Targeting STAT3 with proteolysis targeting chimeras (PROTACs) and next generation antisense oligonucleotides
Signal transducer and activator of transcription 3 (STAT3) has been recognized for its key role in the progression of cancer, where it is frequently upregulated or constitutively hyperactivated, contributing to tumor cell proliferation, survival, and migration, as well as angiogenesis and suppressio...
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| Udgivet i: | Mol Cancer Ther |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7888537/ https://ncbi.nlm.nih.gov/pubmed/33203730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-20-0599 |
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