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Proteolysis targeting chimeras (PROTACs) in cancer therapy
Exploitation of the protein degradation machinery as a therapeutic strategy to degrade oncogenic proteins is experiencing revolutionary advances with the development of proteolysis targeting chimeras (PROTACs). PROTACs are heterobifunctional structures consisting of a ligand that binds a protein to...
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| Publicado no: | J Exp Clin Cancer Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7493969/ https://ncbi.nlm.nih.gov/pubmed/32933565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01672-1 |
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