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PROteolysis TArgeting Chimeras (PROTACs) as emerging anticancer therapeutics
Using PROteolysis TArgeting Chimeras (PROTACs) to degrade proteins that are important for tumorigenesis has emerged as a potential therapeutic strategy for cancer. PROTACs are heterobifunctional molecules consisting of one ligand for binding to a protein of interest (POI) and another to an E3 ubiqui...
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| Publicado no: | Oncogene |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7319888/ https://ncbi.nlm.nih.gov/pubmed/32475992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1336-y |
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