Chargement en cours...

Cholesterol as a modulator of cannabinoid receptor CB(2) signaling

Signaling through integral membrane G protein-coupled receptors (GPCRs) is influenced by lipid composition of cell membranes. By using novel high affinity ligands of human cannabinoid receptor CB(2), we demonstrate that cholesterol increases basal activation levels of the receptor and alters the pha...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Yeliseev, Alexei, Iyer, Malliga R., Joseph, Thomas T., Coffey, Nathan J., Cinar, Resat, Zoubak, Lioudmila, Kunos, George, Gawrisch, Klaus
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7881127/
https://ncbi.nlm.nih.gov/pubmed/33580091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83245-6
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!