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Application of Strep-Tactin XT for affinity purification of Twin-Strep-tagged CB(2), a G protein-coupled cannabinoid receptor

Human cannabinoid receptor CB(2) belongs to the class A of G protein-coupled receptor (GPCR). High resolution structural studies of CB(2) require milligram quantities of purified, structurally intact protein. Here we describe an efficient protocol for purification of this protein using the Twin-Stre...

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Publicat a:Protein Expr Purif
Autors principals: Yeliseev, Alexei, Zoubak, Lioudmila, Schmidt, Thomas G.M.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406253/
https://ncbi.nlm.nih.gov/pubmed/27867058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2016.11.006
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