Cholesterol as a modulator of cannabinoid receptor CB(2) signaling

Signaling through integral membrane G protein-coupled receptors (GPCRs) is influenced by lipid composition of cell membranes. By using novel high affinity ligands of human cannabinoid receptor CB(2), we demonstrate that cholesterol increases basal activation levels of the receptor and alters the pha...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Yeliseev, Alexei, Iyer, Malliga R., Joseph, Thomas T., Coffey, Nathan J., Cinar, Resat, Zoubak, Lioudmila, Kunos, George, Gawrisch, Klaus
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2021
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7881127/
https://ncbi.nlm.nih.gov/pubmed/33580091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83245-6
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