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Cholesterol as a modulator of cannabinoid receptor CB(2) signaling
Signaling through integral membrane G protein-coupled receptors (GPCRs) is influenced by lipid composition of cell membranes. By using novel high affinity ligands of human cannabinoid receptor CB(2), we demonstrate that cholesterol increases basal activation levels of the receptor and alters the pha...
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| Gepubliceerd in: | Sci Rep |
|---|---|
| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group UK
2021
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7881127/ https://ncbi.nlm.nih.gov/pubmed/33580091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83245-6 |
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