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Cholesterol as a modulator of cannabinoid receptor CB(2) signaling
Signaling through integral membrane G protein-coupled receptors (GPCRs) is influenced by lipid composition of cell membranes. By using novel high affinity ligands of human cannabinoid receptor CB(2), we demonstrate that cholesterol increases basal activation levels of the receptor and alters the pha...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7881127/ https://ncbi.nlm.nih.gov/pubmed/33580091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83245-6 |
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