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Cholesterol as a modulator of cannabinoid receptor CB(2) signaling
Signaling through integral membrane G protein-coupled receptors (GPCRs) is influenced by lipid composition of cell membranes. By using novel high affinity ligands of human cannabinoid receptor CB(2), we demonstrate that cholesterol increases basal activation levels of the receptor and alters the pha...
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| 出版年: | Sci Rep |
|---|---|
| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7881127/ https://ncbi.nlm.nih.gov/pubmed/33580091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83245-6 |
| タグ: |
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