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Sarcolipin haploinsufficiency prevents dystrophic cardiomyopathy in mdx mice

Sarcolipin (SLN) is an inhibitor of sarco/endoplasmic reticulum (SR) Ca(2+)-ATPase (SERCA) and expressed at high levels in the ventricles of animal models for and patients with Duchenne muscular dystrophy (DMD). The goal of this study was to determine whether the germline ablation of SLN expression...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Physiol Heart Circ Physiol
Egile Nagusiak: Mareedu, Satvik, Pachon, Ronald, Thilagavathi, Jayapalraj, Fefelova, Nadezhda, Balakrishnan, Rekha, Niranjan, Nandita, Xie, Lai-Hua, Babu, Gopal J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7847070/
https://ncbi.nlm.nih.gov/pubmed/33216625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00601.2020
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