Sarcolipin haploinsufficiency prevents dystrophic cardiomyopathy in mdx mice

Sarcolipin (SLN) is an inhibitor of sarco/endoplasmic reticulum (SR) Ca(2+)-ATPase (SERCA) and expressed at high levels in the ventricles of animal models for and patients with Duchenne muscular dystrophy (DMD). The goal of this study was to determine whether the germline ablation of SLN expression...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Mareedu, Satvik, Pachon, Ronald, Thilagavathi, Jayapalraj, Fefelova, Nadezhda, Balakrishnan, Rekha, Niranjan, Nandita, Xie, Lai-Hua, Babu, Gopal J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7847070/
https://ncbi.nlm.nih.gov/pubmed/33216625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00601.2020
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