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Sarcolipin haploinsufficiency prevents dystrophic cardiomyopathy in mdx mice

Sarcolipin (SLN) is an inhibitor of sarco/endoplasmic reticulum (SR) Ca(2+)-ATPase (SERCA) and expressed at high levels in the ventricles of animal models for and patients with Duchenne muscular dystrophy (DMD). The goal of this study was to determine whether the germline ablation of SLN expression...

詳細記述

保存先:
書誌詳細
出版年:Am J Physiol Heart Circ Physiol
主要な著者: Mareedu, Satvik, Pachon, Ronald, Thilagavathi, Jayapalraj, Fefelova, Nadezhda, Balakrishnan, Rekha, Niranjan, Nandita, Xie, Lai-Hua, Babu, Gopal J.
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7847070/
https://ncbi.nlm.nih.gov/pubmed/33216625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00601.2020
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