Sarcolipin haploinsufficiency prevents dystrophic cardiomyopathy in mdx mice

Sarcolipin (SLN) is an inhibitor of sarco/endoplasmic reticulum (SR) Ca(2+)-ATPase (SERCA) and expressed at high levels in the ventricles of animal models for and patients with Duchenne muscular dystrophy (DMD). The goal of this study was to determine whether the germline ablation of SLN expression...

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Detaylı Bibliyografya
Yayımlandı:Am J Physiol Heart Circ Physiol
Asıl Yazarlar: Mareedu, Satvik, Pachon, Ronald, Thilagavathi, Jayapalraj, Fefelova, Nadezhda, Balakrishnan, Rekha, Niranjan, Nandita, Xie, Lai-Hua, Babu, Gopal J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2021
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7847070/
https://ncbi.nlm.nih.gov/pubmed/33216625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00601.2020
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