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Ablation of phospholamban and sarcolipin results in cardiac hypertrophy and decreased cardiac contractility
AIMS: Improving the sarco(endo)plasmic reticulum (SR) Ca(2+)-ATPase (SERCA) function has clinical implications in treating heart failure. The present study aimed to determine the effect of constitutive activation of the SERCA pump on cardiac contractility in normal mice and during pressure-overload-...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3020129/ https://ncbi.nlm.nih.gov/pubmed/20833651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvq294 |
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