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Sarcolipin deletion in mdx mice impairs calcineurin signalling and worsens dystrophic pathology
Duchenne muscular dystrophy (DMD) is the most severe form of muscular dystrophy affecting 1 in 3500 live male births. Although there is no cure for DMD, therapeutic strategies aimed at enhancing calcineurin signalling and promoting the slow fibre phenotype have shown promise in mdx mice, which is th...
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| Pubblicato in: | Hum Mol Genet |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6240731/ https://ncbi.nlm.nih.gov/pubmed/30137316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy302 |
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