Sarcolipin deletion in mdx mice impairs calcineurin signalling and worsens dystrophic pathology

Duchenne muscular dystrophy (DMD) is the most severe form of muscular dystrophy affecting 1 in 3500 live male births. Although there is no cure for DMD, therapeutic strategies aimed at enhancing calcineurin signalling and promoting the slow fibre phenotype have shown promise in mdx mice, which is th...

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Bibliografiska uppgifter
I publikationen:Hum Mol Genet
Huvudupphovsmän: Fajardo, Val A, Chambers, Paige J, Juracic, Emma S, Rietze, Bradley A, Gamu, Daniel, Bellissimo, Catherine, Kwon, Frenk, Quadrilatero, Joe, Russell Tupling, A
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2018
Ämnen:
General Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240731/
https://ncbi.nlm.nih.gov/pubmed/30137316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy302
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