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Sarcolipin deletion in mdx mice impairs calcineurin signalling and worsens dystrophic pathology

Duchenne muscular dystrophy (DMD) is the most severe form of muscular dystrophy affecting 1 in 3500 live male births. Although there is no cure for DMD, therapeutic strategies aimed at enhancing calcineurin signalling and promoting the slow fibre phenotype have shown promise in mdx mice, which is th...

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書目詳細資料
發表在:Hum Mol Genet
Main Authors: Fajardo, Val A, Chambers, Paige J, Juracic, Emma S, Rietze, Bradley A, Gamu, Daniel, Bellissimo, Catherine, Kwon, Frenk, Quadrilatero, Joe, Russell Tupling, A
格式: Artigo
語言:Inglês
出版: Oxford University Press 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240731/
https://ncbi.nlm.nih.gov/pubmed/30137316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy302
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