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Allele-specific role of ERBB2 in the oncogenic function of EGFR L861Q in EGFR-mutant lung cancers
INTRODUCTION: Unlike common EGFR mutations, many less common EGFR mutations remain poorly characterized in terms of oncogenic function and drug sensitivity. Herein, we characterize the subset of lung adenocarcinoma harboring EGFR L861Q through both preclinical and clinical investigations. EXPERIMENT...
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| Publicado no: | J Thorac Oncol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7775889/ https://ncbi.nlm.nih.gov/pubmed/33038514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2020.09.019 |
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