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Discovery of Homobivalent Bitopic Ligands of the Cannabinoid CB(2) Receptor
Single chemical entities with potential to simultaneously interact with two binding sites are emerging strategies in medicinal chemistry. We have designed, synthesized and functionally characterized the first bitopic ligands for the CB(2) receptor. These compounds selectively target CB(2) versus CB(...
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| 發表在: | Chemistry |
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| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
John Wiley and Sons Inc.
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7756656/ https://ncbi.nlm.nih.gov/pubmed/32794211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202003389 |
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