Discovery of Homobivalent Bitopic Ligands of the Cannabinoid CB(2) Receptor

Single chemical entities with potential to simultaneously interact with two binding sites are emerging strategies in medicinal chemistry. We have designed, synthesized and functionally characterized the first bitopic ligands for the CB(2) receptor. These compounds selectively target CB(2) versus CB(...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Chemistry
Asıl Yazarlar: Morales, Paula, Navarro, Gemma, Gómez‐Autet, Marc, Redondo, Laura, Fernández‐Ruiz, Javier, Pérez‐Benito, Laura, Cordomí, Arnau, Pardo, Leonardo, Franco, Rafael, Jagerovic, Nadine
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2020
Konular:
Communications
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7756656/
https://ncbi.nlm.nih.gov/pubmed/32794211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202003389
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