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Benzyl-1,2,4-triazoles as CB(1) Cannabinoid Receptor Ligands: Preparation and In Vitro Pharmacological Evaluation
In a previous study, we have identified 3-alkyl-1,5-diaryl-1H-1,2,4-triazoles to be a novel class of cannabinoid type 1 receptor (CB(1)R) antagonists. In order to expand the number of cannabinoid ligands with a central 1,2,4-triazole scaffold, we have synthesized a novel series of 1-benzyl-1H-1,2,4-...
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| Publicado no: | Int J Med Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4834188/ https://ncbi.nlm.nih.gov/pubmed/27127651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1257098 |
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