Benzyl-1,2,4-triazoles as CB(1) Cannabinoid Receptor Ligands: Preparation and In Vitro Pharmacological Evaluation

In a previous study, we have identified 3-alkyl-1,5-diaryl-1H-1,2,4-triazoles to be a novel class of cannabinoid type 1 receptor (CB(1)R) antagonists. In order to expand the number of cannabinoid ligands with a central 1,2,4-triazole scaffold, we have synthesized a novel series of 1-benzyl-1H-1,2,4-...

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Dettagli Bibliografici
Pubblicato in:Int J Med Chem
Autori principali: Hernandez-Folgado, Laura, Decara, Juan, Rodríguez de Fonseca, Fernando, Goya, Pilar, Jagerovic, Nadine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2016
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834188/
https://ncbi.nlm.nih.gov/pubmed/27127651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1257098
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