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Allosteric Modulators of the CB(1) Cannabinoid Receptor: A Structural Update Review

In 2005, the first evidence of an allosteric binding site at the CB(1)R was provided by the identification of three indoles of the company Organon that were allosteric enhancers of agonist binding affinity and, functionally, allosteric inhibitors of agonist activity. Since then, structure–activity r...

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Pubblicato in:Cannabis Cannabinoid Res
Autori principali: Morales, Paula, Goya, Pilar, Jagerovic, Nadine, Hernandez-Folgado, Laura
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576597/
https://ncbi.nlm.nih.gov/pubmed/28861476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/can.2015.0005
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