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Allosteric Modulators of the CB(1) Cannabinoid Receptor: A Structural Update Review

In 2005, the first evidence of an allosteric binding site at the CB(1)R was provided by the identification of three indoles of the company Organon that were allosteric enhancers of agonist binding affinity and, functionally, allosteric inhibitors of agonist activity. Since then, structure–activity r...

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Detalhes bibliográficos
Publicado no:Cannabis Cannabinoid Res
Main Authors: Morales, Paula, Goya, Pilar, Jagerovic, Nadine, Hernandez-Folgado, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576597/
https://ncbi.nlm.nih.gov/pubmed/28861476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/can.2015.0005
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