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Cannabidiol is a negative allosteric modulator of the cannabinoid CB(1) receptor

BACKGROUND AND PURPOSE: Cannabidiol has been reported to act as an antagonist at cannabinoid CB(1) receptors. We hypothesized that cannabidiol would inhibit cannabinoid agonist activity through negative allosteric modulation of CB(1) receptors. EXPERIMENTAL APPROACH: Internalization of CB(1) recepto...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Br J Pharmacol
Päätekijät: Laprairie, R B, Bagher, A M, Kelly, M E M, Denovan‐Wright, E M
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621983/
https://ncbi.nlm.nih.gov/pubmed/26218440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13250
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