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Cannabidiol is a negative allosteric modulator of the cannabinoid CB(1) receptor
BACKGROUND AND PURPOSE: Cannabidiol has been reported to act as an antagonist at cannabinoid CB(1) receptors. We hypothesized that cannabidiol would inhibit cannabinoid agonist activity through negative allosteric modulation of CB(1) receptors. EXPERIMENTAL APPROACH: Internalization of CB(1) recepto...
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| Опубликовано в: : | Br J Pharmacol |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4621983/ https://ncbi.nlm.nih.gov/pubmed/26218440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13250 |
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