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Novel analogs of PSNCBAM-1 as allosteric modulators of cannabinoid CB1 receptor
In this work, we explored the molecular framework of the known CB1R allosteric modulator PSNCBAM-1 with the aim to generate new bioactive analogs and to deepen the structure-activity relationships of this type of compounds. In particular, the introduction of a NH group between the pyridine ring and...
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| Udgivet i: | Bioorg Med Chem |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5794004/ https://ncbi.nlm.nih.gov/pubmed/29079014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2017.10.015 |
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