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Structural Optimization of the Diarylurea PSNCBAM-1, an Allosteric Modulator of Cannabinoid Receptor 1
BACKGROUND: Structure–activity relationship studies improve the pharmacological and pharmacokinetic properties of a lead compound such as PSNCBAM-1, an allosteric modulator of the cannabinoid receptor 1. OBJECTIVES: Here, several derivatives of PSNCBAM-1 were synthesized with the aim of reducing the...
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| Publicado en: | Curr Ther Res Clin Exp |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Elsevier
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6994307/ https://ncbi.nlm.nih.gov/pubmed/32021660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.curtheres.2019.100574 |
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