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Translational potential of allosteric modulators targeting the cannabinoid CB(1) receptor

The cannabinoid type-1 (CB(1)) receptor, a G-protein-coupled receptor, is an attractive target for drug discovery due to its involvement in many physiological processes. Historically, drug discovery efforts targeting the CB(1) receptor have focused on the development of orthosteric ligands that inte...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Lu, Dai, Immadi, Sri Sujana, Wu, Zhixing, Kendall, Debra A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6460365/
https://ncbi.nlm.nih.gov/pubmed/30333554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-018-0164-x
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