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Translational potential of allosteric modulators targeting the cannabinoid CB(1) receptor

The cannabinoid type-1 (CB(1)) receptor, a G-protein-coupled receptor, is an attractive target for drug discovery due to its involvement in many physiological processes. Historically, drug discovery efforts targeting the CB(1) receptor have focused on the development of orthosteric ligands that inte...

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Detalles Bibliográficos
Publicado en:Acta Pharmacol Sin
Main Authors: Lu, Dai, Immadi, Sri Sujana, Wu, Zhixing, Kendall, Debra A.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6460365/
https://ncbi.nlm.nih.gov/pubmed/30333554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-018-0164-x
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