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Translational potential of allosteric modulators targeting the cannabinoid CB(1) receptor

The cannabinoid type-1 (CB(1)) receptor, a G-protein-coupled receptor, is an attractive target for drug discovery due to its involvement in many physiological processes. Historically, drug discovery efforts targeting the CB(1) receptor have focused on the development of orthosteric ligands that inte...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Acta Pharmacol Sin
Hauptverfasser: Lu, Dai, Immadi, Sri Sujana, Wu, Zhixing, Kendall, Debra A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6460365/
https://ncbi.nlm.nih.gov/pubmed/30333554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-018-0164-x
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