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Cannabidiol is a negative allosteric modulator of the cannabinoid CB(1) receptor

BACKGROUND AND PURPOSE: Cannabidiol has been reported to act as an antagonist at cannabinoid CB(1) receptors. We hypothesized that cannabidiol would inhibit cannabinoid agonist activity through negative allosteric modulation of CB(1) receptors. EXPERIMENTAL APPROACH: Internalization of CB(1) recepto...

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書目詳細資料
發表在:Br J Pharmacol
Main Authors: Laprairie, R B, Bagher, A M, Kelly, M E M, Denovan‐Wright, E M
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2015
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621983/
https://ncbi.nlm.nih.gov/pubmed/26218440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13250
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