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Allosteric Modulators of the CB(1) Cannabinoid Receptor: A Structural Update Review

In 2005, the first evidence of an allosteric binding site at the CB(1)R was provided by the identification of three indoles of the company Organon that were allosteric enhancers of agonist binding affinity and, functionally, allosteric inhibitors of agonist activity. Since then, structure–activity r...

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Dades bibliogràfiques
Publicat a:Cannabis Cannabinoid Res
Autors principals: Morales, Paula, Goya, Pilar, Jagerovic, Nadine, Hernandez-Folgado, Laura
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576597/
https://ncbi.nlm.nih.gov/pubmed/28861476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/can.2015.0005
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