Targeting Cannabinoid CB(2) Receptors in the Central Nervous System. Medicinal Chemistry Approaches with Focus on Neurodegenerative Disorders

Endocannabinoids activate two types of specific G-protein-coupled receptors (GPCRs), namely cannabinoid CB(1) and CB(2). Contrary to the psychotropic actions of agonists of CB(1) receptors, and serious side effects of the selective antagonists of this receptor, drugs acting on CB(2) receptors appear...

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Vydáno v:Front Neurosci
Hlavní autoři: Navarro, Gemma, Morales, Paula, Rodríguez-Cueto, Carmen, Fernández-Ruiz, Javier, Jagerovic, Nadine, Franco, Rafael
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2016
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020102/
https://ncbi.nlm.nih.gov/pubmed/27679556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2016.00406
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