Targeting Cannabinoid CB(2) Receptors in the Central Nervous System. Medicinal Chemistry Approaches with Focus on Neurodegenerative Disorders

Endocannabinoids activate two types of specific G-protein-coupled receptors (GPCRs), namely cannabinoid CB(1) and CB(2). Contrary to the psychotropic actions of agonists of CB(1) receptors, and serious side effects of the selective antagonists of this receptor, drugs acting on CB(2) receptors appear...

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Bibliographic Details
Published in:Front Neurosci
Main Authors: Navarro, Gemma, Morales, Paula, Rodríguez-Cueto, Carmen, Fernández-Ruiz, Javier, Jagerovic, Nadine, Franco, Rafael
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020102/
https://ncbi.nlm.nih.gov/pubmed/27679556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2016.00406
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