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Targeting Cannabinoid CB(2) Receptors in the Central Nervous System. Medicinal Chemistry Approaches with Focus on Neurodegenerative Disorders

Endocannabinoids activate two types of specific G-protein-coupled receptors (GPCRs), namely cannabinoid CB(1) and CB(2). Contrary to the psychotropic actions of agonists of CB(1) receptors, and serious side effects of the selective antagonists of this receptor, drugs acting on CB(2) receptors appear...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Neurosci
Prif Awduron: Navarro, Gemma, Morales, Paula, Rodríguez-Cueto, Carmen, Fernández-Ruiz, Javier, Jagerovic, Nadine, Franco, Rafael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020102/
https://ncbi.nlm.nih.gov/pubmed/27679556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2016.00406
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