Synergistic activation of AMPK prevents from polyglutamine-induced toxicity in Caenorhabditis elegans

Expression of abnormally long polyglutamine (polyQ) tracks is the source of a range of dominant neurodegenerative diseases, such as Huntington disease. Currently, there is no treatment for this devastating disease, although some chemicals, e.g., metformin, have been proposed as therapeutic solutions...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Pharmacol Res
Autors principals: Gómez-Escribano, AP, Bono-Yagüe, J, García-Gimeno, MA, Sequedo, MD, Hervás, D, Fornés-Ferrer, V, Torres-Sánchez, SC, Millán, JM, Sanz, P, Vázquez-Manrique, RP
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7755709/
https://ncbi.nlm.nih.gov/pubmed/32739430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2020.105105
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars