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Synergistic activation of AMPK prevents from polyglutamine-induced toxicity in Caenorhabditis elegans
Expression of abnormally long polyglutamine (polyQ) tracks is the source of a range of dominant neurodegenerative diseases, such as Huntington disease. Currently, there is no treatment for this devastating disease, although some chemicals, e.g., metformin, have been proposed as therapeutic solutions...
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| Publicado no: | Pharmacol Res |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7755709/ https://ncbi.nlm.nih.gov/pubmed/32739430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2020.105105 |
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